Dementia in patients with diabetes mellitus

Lena Sovi E Sitorus, N. K. S. Diniari, R. Kuswardhani
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Abstract

The role of diabetes mellitus in neurodegeneration has been confirmed by neuroimaging and neuropathological studies. Apart from causing schizophrenia, chronic exposure to hyperglycemia may worsen cognitive function and cause significant cognitive disorders, such as Alzheimer’s and dementia. An 81-year-old woman was consulted to the Psychiatry department with fatigue and forgetfulness. She was found unconscious in her room. In the emergency room, her blood glucose level was 30 mg/dl with type 2 diabetes since 2012. She was able to pronounce her name correctly but forgot her age, said that she was in her home, the examinations were in the morning, and the name of her ex-employee who accompanied her and said that she already had breakfast, could repeat the names of 3 objects given. She  was asked to repeat in 1 minute  can only say 1 name of the object correctly, cannot count the subtraction several times. The patient correctly pronounced the name of the object shown to her, but cannot fold paper, write sentences, or draw. Psychiatrist give her Avram 1x5 mg and Aricept 1x5 mg also provided assistance, family education, and reminiscence therapy, and she had 8 units of Novorapid injection subcutaneously after a meal from the geriatrist.
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糖尿病患者的痴呆
糖尿病在神经变性中的作用已被神经影像学和神经病理学研究证实。除了导致精神分裂症外,长期暴露于高血糖还可能使认知功能恶化,并导致严重的认知障碍,如阿尔茨海默氏症和痴呆症。一位81岁的妇女因疲劳和健忘被咨询到精神科。人们发现她在房间里不省人事。在急诊室,她的血糖水平为30毫克/分升,自2012年以来患有2型糖尿病。她能够正确地读出自己的名字,但忘记了自己的年龄,她说她在家里,考试是在早上,她的前雇员的名字陪着她,她说她已经吃过早餐了,她能重复给出的3个物体的名字。她被要求在1分钟内重复只能正确说出1个物体的名字,不能数几次减法。病人能正确地读出展示给她的物体的名字,但不能折纸、写句子或画画。精神科给予阿夫拉姆1x5 mg、阿拉西普1x5 mg,并给予协助、家庭教育、回忆治疗,老年科医师餐后给予诺伐快皮下注射8单位。
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