A Review of Inpatient Opioid Consumption and Discharge Prescription Patterns After Orthopaedic Procedures.

T. Grace, K. Choo, Joseph T. Patterson, Krishn Khanna, B. Feeley, Alan L. Zhang
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引用次数: 12

Abstract

INTRODUCTION Tailoring opioid prescriptions to inpatient use after orthopaedic procedures may effectively control pain while limiting overprescription but may not be common in the current orthopaedic practice. METHODS A retrospective review identified opioid-naïve patients admitted after any orthopaedic procedure. Daily and total prescription quantities as well as patient-specific factors were collected. The total opioids used the day before discharge was compared with the total opioids prescribed for the day after discharge. Refill rates were then compared between patients whose daily discharge prescription regimen far exceeded or approximated their predischarge opioid consumption. RESULTS Six hundred thirteen patients were included (ages 18 to 95 years). The total opioids prescribed for the 24 hours after discharge significantly exceeded the opioids consumed the 24 hours before discharge for each orthopaedic subspecialty. The excessive-prescription group (409 patients) received greater daily opioid (120 oral morphine equivalents [OMEs] versus 60 OMEs; P < 0.01) and total opioid (750 OMEs versus 512.5 OMEs; P < 0.01) at discharge but was more likely to refill their opioid prescription within 30 days of discharge (27.6% versus 20.1%; P = 0.043). DISCUSSION Opioid regimens prescribed after an orthopaedic surgery frequently exceed inpatient opioid use. Opioid regimens that approximate inpatient use may help curb overprescription and are not associated with higher refill rates compared with more excessive prescriptions. LEVEL OF EVIDENCE Level III, Retrospective Cohort Study.
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骨科手术后住院阿片类药物消耗和出院处方模式的回顾。
根据骨科手术后住院患者的使用量身定制阿片类药物处方可以有效地控制疼痛,同时限制过度处方,但在目前的骨科实践中可能并不常见。方法回顾性分析所有骨科手术后入院的opioid-naïve患者。收集每日处方量和总处方量以及患者特异性因素。将出院前一天的总阿片类药物用量与出院后一天的总阿片类药物用量进行比较。然后比较每日出院处方方案远远超过或接近其出院前阿片类药物消耗量的患者的补充率。结果纳入613例患者(年龄18 ~ 95岁)。各骨科专科出院后24小时的阿片类药物处方总量明显超过出院前24小时的阿片类药物消耗量。过量处方组(409名患者)每天接受更多的阿片类药物(120口服吗啡当量[OMEs]对60口服吗啡当量;P < 0.01)和总阿片类药物(750个ome vs 512.5个ome;P < 0.01),但更有可能在出院30天内重新服用阿片类药物处方(27.6%比20.1%;P = 0.043)。骨科手术后开具的阿片类药物治疗方案经常超过住院患者阿片类药物的使用。近似于住院患者使用的阿片类药物方案可能有助于遏制过度处方,并且与更多过量处方相比,与更高的再填充率无关。证据水平:III级,回顾性队列研究。
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