Preoperative Right Ventricular Echocardiographic Parameters Predict Perioperative Cardiovascular Complications in Patients Undergoing High risk Non-Cardiac Surgery

Mohammed Suleiman Mohammed, W. Atia, Alyaa Zahran
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Abstract

Background : Every year, 200 million people worldwide undergo major noncardiac surgery (NCS), and 10 million people experience a signi fi cant cardiac problem during the fi rst 30 days following NCS. Perioperative cardiovascular complications (PCCs) are extremely signi fi cant as they contribute to at least one-third of perioperative mortality, lengthen hospital stays, and raise medical expenses. Objective : The aim was to investigate the importance of presurgical right ventricular (RV) echocardiographic parameters in the prediction of PCCs in individuals having high-risk NCS. Patients and methods : In this prospective cohort observational trial, 200 patients who were all potential candidates for high-risk, noncardiac operations between October 2020 and June 2021 were included. Patients were allocated preoperatively into one group and postoperatively into two groups according to the presence of postoperative cardiac complications. Results : The incidence of PPCs among the study population was about 36 patients of 200 patients with percentage of 18%. The results also revealed that signi fi cant predictors of postoperative PCCs after major NCS arranged by descending manner according to their odds ratio are as follows: Tie index greater than 0.47, tricuspid valve E/A (TV E/A) less than or equal to 1.18, tricuspid annular plane systolic excursion less than or equal to 1.8, MV E/A less than or equal to 1.3, left ventricular ejection fraction (LVEF) (%) less than or equal to 56, LVESDV (ml 3 ) greater than 35.6, HbA1C greater than 7.7, MV E/e ′ greater than 8.32, revised cardiac risk index, RV fractional area change (%) less than or equal to 35.6, mitral regurgitation (MR) up to moderate, serum creatinine (mg/dl) greater than 1.4, left atrial volume index (LAVI) greater than 22, and serum urea (mg/dl) greater than 34. By multivariate analysis, the authors found that the signi fi cant risk factors for PCCs are LVEF (%) less than or equal to 56, TV E/A less than or equal to 1.18, and Tie index greater than 0.47. Conclusion : RV echocardiographic measures taken before surgery are independent risk factors for PCCs in individuals having major NCS.
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术前右心室超声心动图参数预测高危非心脏手术患者围手术期心血管并发症
背景:每年,全世界有2亿人接受重大非心脏手术(NCS), 1000万人在NCS后的前30天内出现严重的心脏问题。围手术期心血管并发症(PCCs)是非常重要的,因为它们至少占围手术期死亡率的三分之一,延长住院时间并增加医疗费用。目的:探讨术前右心室(RV)超声心动图参数在高危NCS患者PCCs预测中的重要性。患者和方法:在这项前瞻性队列观察性试验中,纳入了200名患者,这些患者都是2020年10月至2021年6月期间高危非心脏手术的潜在候选者。根据患者术后心脏并发症情况,术前分为一组,术后分为两组。结果:200例患者中PPCs发生率约36例,占18%。结果还显示,根据比值比降序排列的重大NCS术后PCCs的显著预测因子如下:领带指数大于0.47,三尖瓣E / A(电视E / A)小于或等于1.18,三尖瓣环平面收缩偏差小于或等于1.8 MV E /小于或等于1.3,左心室射血分数(LVEF)(%)小于或等于56岁LVESDV(毫升3)大于35.6,糖化血红蛋白大于7.7,MV E / E”大于8.32,修订后的心脏风险指数RV部分区域变化(%)小于或等于35.6,中度二尖瓣返流(MR),血清肌酐(mg/dl) > 1.4,左房容积指数(LAVI) > 22,血清尿素(mg/dl) > 34。通过多因素分析,笔者发现PCCs的显著危险因素为LVEF(%)≤56,TV E/A≤1.18,Tie指数> 0.47。结论:术前RV超声心动图检查是严重NCS患者发生PCCs的独立危险因素。
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