51 Korsakoff’s psychosis: is polypharmacy a concern?

K. O'driscoll, Tayler Sulse, Emily M. Huston, P. Byrne, J. Hoblyn
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Abstract

Objectives/Aims Case studies of all current Inpatients with Korsakoff’s Syndrome in a 114 bed Psychiatric Hospital. Methods Audit and review of 114 individuals residing in a long stay Psychiatric Hospital during 2018. Medical records and Pharmacy Data base were reviewed to identify co-morbidities and medication exposure. Results Thirteen individuals were identified with the formal diagnosis of Korsakoff’s syndrome. Five were female with and age range from 51 years to 84 years. Eight were male with an age range from 55 to 84 years. Conclusions Careful consideration must continue to minimize polypharmacy. KS patients have complex comorbid health conditions. Careful consideration of potential interactions, disabling side effects, potential adverse reactions and collaboration with a Pharmacist is invaluable. References Kopelman M.D., Thomson, A.D., Guerrini, I., Marshall, E.J. The Korsakoff Syndrome: Clinical Aspects, Psychology and Treatment. Alcohol & Alcoholism 2009;44(2):148–154. Johnson, J.M., and Fox, V. Beyond Thiamine: Treatment for Cognitive Impairment in Korsakoff’s Syndrome. Psychosomatics 2018;59(4):311–317.
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51科萨科夫的精神病:多重用药是个问题吗?
目的/目的对某114张床位的精神病院所有科萨科夫综合征住院患者进行病例研究。方法对2018年长期住院精神病院114例患者进行审计和回顾。对医疗记录和药学数据库进行审查,以确定合并症和药物暴露。结果13例确诊为科尔萨科夫综合征。女性5例,年龄51 ~ 84岁。8名男性,年龄从55岁到84岁不等。结论必须继续谨慎考虑尽量减少多药。KS患者有复杂的合并症。仔细考虑潜在的相互作用,致残的副作用,潜在的不良反应和与药剂师的合作是非常宝贵的。参考文献Kopelman m.d., Thomson, a.d., Guerrini, I., Marshall, E.J. Korsakoff综合征:临床方面,心理学和治疗。酒精与酒精中毒2009;44(2):148-154。Johnson, j.m.和Fox, V.《超越硫胺素:Korsakoff综合征认知障碍的治疗》。心身医学2018;59(4):311 - 317。
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