Prevalence and Associated Factors of Obsessive-Compulsive Disorder in Egyptian Adolescents

H. Gabr, A. Elhadad, S. A. Raouf, Ghadeer M El, Sheikh
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Abstract

Background: Obsessive compulsive disorder (OCD) is a burdensome disorder which is increasingly becoming the focus of interest in adolescent psychiatry due to its impact on the quality of life. Objective: to assess the prevalence and associated factors of obsessivecompulsive disorder in Egyptian adolescents. Method: A nested case control study (cross sectional study followed by case control study) was conducted on 1574 students from Menoufia governorate, Egypt. The participants were selected from secondary schools using multistage random sample. OCD was diagnosed using Yale-Brown ObsessiveCompulsive Scale. Arabic version of the Wechsler Adult Intelligence Scale-IV was used to measure intelligence and cognitive ability in cases with OCD. Results: The prevalence of OCD was 3.24%. There was a statistically significant difference between OCD cases and control, being higher in urban areas (OR 2.43, 95% CI 1.09–5.43), high socioeconomic standard (SES) (OR 2.95, 95% CI 1.24–7.06), positive family history (OR 4.40, 95% CI 1.91–10.11) and the absence of close friend (OR 2.22, 95% CI 1.00–4.91). There was non-significant statistical difference between OCD cases and control regarding total IQ score and verbal IQ, but the performance IQ (PIQ) showed significant difference between the two groups being lower in OCD cases. On logistic regression, the predictors for OCD were high SES, positive family history, absence of close friend and low PIQ. Conclusion: OCD was found to be prevalent among adolescents. Urban residence, high SES, positive family history, the absence of close friend and low PIQ were significantly associated with OCD.
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埃及青少年强迫症的患病率及相关因素
背景:强迫症(OCD)是一种负担沉重的疾病,由于其对生活质量的影响而日益成为青少年精神病学关注的焦点。目的:了解埃及青少年强迫症的患病率及相关因素。方法:对埃及Menoufia省1574名学生进行巢式病例对照研究(横断面研究后病例对照研究)。研究对象采用多阶段随机抽样的方法从中学中抽取。强迫症诊断采用耶鲁-布朗强迫症量表。使用阿拉伯语版韦氏成人智力量表- iv来测量强迫症患者的智力和认知能力。结果:强迫症的患病率为3.24%。OCD病例与对照组之间的差异有统计学意义,在城市地区(OR 2.43, 95% CI 1.09-5.43)、高社会经济标准(OR 2.95, 95% CI 1.24-7.06)、阳性家族史(OR 4.40, 95% CI 1.91-10.11)和缺乏亲密朋友(OR 2.22, 95% CI 1.00-4.91)中较高。强迫症组与对照组在总智商和语言智商方面差异无统计学意义,但在行为智商(PIQ)方面差异有统计学意义,强迫症组较低。logistic回归分析显示,高社会经济地位、阳性家族史、缺乏亲密朋友和低智商是强迫症的预测因素。结论:强迫症在青少年中普遍存在。城市居住、高社会经济地位、阳性家族史、缺乏亲密朋友和低PIQ与强迫症有显著相关。
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