A Case of Laryngeal Amyloidosis

Abstract

Amyloidosis accounts for less than 1% of all benign tumors of the larynx. We herein report a case of supraglottic amyloidosis in the larynx. A37 -year-old male presented with a three-year history of hoarseness of voice. The initial examination revealed a tumor with a smooth surface on the left false vocal cord, with intact vocal cord mobility. We subsequently performed laryngomicrosurgery and resected the tumor. Histopathologically, the specimen showed submucosal deposition of amyloid with hematoxylin and Congo red staining. A diagnosis of systemic amyloidosis was excluded on follow-up examinations. The patient’s voice quality improved, and with no episodes of recurrence for five years after the surgery. Amyloidosis of the larynx is a rare and usually benign condition. However, long-term follow-up is required in such cases, as the disease may recur a long time after treatment.