Lifestyle, Physical and Cardiovascular Components Associated with Immune Profile in Hispanic-Latino People Living with HIV

Abstract

Associated Profile Abstract H IV is associated with poor quality of life and high mortality rates on the people suffering from this illness. Presently, Cd4 levels are the main factor established to identify the distinct trauma on the host’s body and systems. The consequence and severity of HIV complications vary among individuals; however, many factors come into play when assessing and developing treatment plans for this population. Purpose: The current investigation endeavors to respond to the following, are there any indicators of a weak immune system other than a low Cd4 count in people living with HIV (PLHIV) that can aid and guide more target treatment to increase life expectancy and improve quality of life? This project's invention is to establish a comprehensive profile equated with the immune system levels among Hispanics-Latino PLHIV. Methods: Data was extracted and collected from 449 partakers' records from participants enrolled in La Perla de Gran Precio HIV Community Center in Puerto Rico. We examined and compared the relationship between five distinct components, motor (speed and inclination on a treadmill), cardiorespiratory (cardio time and HR), lipid panel (triglycerides, cholesterol among others), comorbidities (diabetes, neuropathy, among others) and lifestyle (smoker, sedentary, etc.), which are essential physical fitness components, regarding subjects’ immune profiles (Cd4 values). Results: The data analyzed in this study were from 449 participants' records further divided into 198 for the Low-HIV (Cd4=323.6+/-120.75) and 247 for the High-HIV (Cd4=836.84+/-283.41) groups according to Cd4 values. The L-HIV and H-HIV were, for the most part, males with an average age of 54 years old and approximately 20 years of diagnosis. An ANOVA analysis revealed that four out of the five components showed differences among both groups. Conclusion: In Hispanic Latino PLHIV, distinctive physical and cardiovascular profiles, related to lower immune health, were identified. We recommend adding the components mentioned in this study to comprehensively understand the mechanism affecting the quality of life and life expectancy in those with HIV.