A contact lens sensor system with a micro-capacitor for wireless intraocular pressure monitoring

Yu-Chieh Huang, Guan-Ting Yeh, Tzu-Sen Yang, J. Chiou
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引用次数: 19

Abstract

This paper proposes a novel micro-capacitor sensor for intraocular pressure (IOP) measurement on soft contact lens. The sensor was designed and fabricated by using MEMS fabrication technologies. The contact lens is for wearing on a cornea such that a curvature of the contact lens corresponds substantially to that of the cornea, and is preferably made of Hydroxyethylmethacrylate (HEMA) by cast-molding method of soft contact lens for high oxygen permeability and comfortable long-duration wearing. The prototype without wireless antenna has been implemented with a sensitivity of 0.43 pF/mmHg in measurement of human eye like balloon pressure test between 100 mmHg and 180 mmHg. The results show its high stability and reproducibility in a series of repeatable pressure variation. In future work the micro-capacitor will be tested on enucleated porcine eyes with better and integrated with a radio frequency integrated circuit and antenna on soft contact lens so that IOP value could be transferred to voltage value via capacitor to voltage converter and transmits IOP sensing signal by wireless telemetry system.
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一种带微电容的隐形眼镜传感器系统,用于无线眼压监测
提出了一种用于软性隐形眼镜眼内压测量的新型微电容传感器。该传感器采用MEMS制造技术进行设计和制造。该隐形眼镜用于佩戴在角膜上,使得所述隐形眼镜的曲率基本上与所述角膜的曲率相对应,优选地由高透氧性和舒适长时间佩戴的软性隐形眼镜的浇铸成型方法制成的羟乙基甲基丙烯酸酯(HEMA)。无无线天线的样机已实现,灵敏度为0.43 pF/mmHg,可用于人眼样球囊压力测试,测量范围为100 ~ 180 mmHg。结果表明,该方法在一系列可重复的压力变化中具有较高的稳定性和重现性。在今后的工作中,微型电容器将在去核猪眼上进行测试,并与射频集成电路和软性隐形眼镜上的天线集成,通过电容器-电压转换器将IOP值转换为电压值,并通过无线遥测系统传输IOP传感信号。
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