Delayed pubertal growth spurt in glomerulopathic boys receiving alternate-day prednisone.

Child nephrology and urology Pub Date : 1992-01-01
C Polito, R Di Toro
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引用次数: 0

Abstract

Statural growth was studied in 16 glomerulopathic children, 12 boys and 4 girls, treated with alternate-day prednisone for more than 2 years. Five patients were older than 12 years when started on therapy. Growth velocity was significantly slower in boys who received therapy during peripubertal age than in younger boys taking similar amounts of prednisone. In boys, pubertal growth spurt was delayed and shorter than normal, but growth continued with a velocity greater than normal for some years and kept on after 19 years of age. The ultimate height of the patients followed up after 19 years of age ranged within the normal limits of genetic height potential.

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接受隔日强的松治疗的肾小球病男孩的青春期生长突增延迟。
研究了16例肾小球病患儿(12例男孩,4例女孩)的体格生长情况,这些患儿采用隔日强的松治疗2年以上。5名患者在开始治疗时年龄超过12岁。在青春期周围接受治疗的男孩的生长速度明显慢于服用相同剂量强的松的年轻男孩。在男孩中,青春期的生长突增比正常的要延迟和短,但在一些年里,生长的速度比正常的要快,并在19岁以后继续保持。19岁后随访的患者最终身高均在遗传身高潜能的正常范围内。
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