Efficacy of CAPD as the primary treatment for end-stage renal failure in children.

Child nephrology and urology Pub Date : 1992-01-01
M Barakat, J M Savage, A Burns, M Stewart
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Abstract

In the 6 years before this paper, all children presenting with end-stage renal failure (ESRF) in Northern Ireland were electively commenced on continuous ambulatory peritoneal dialysis (CAPD). In that period, 22 patients were treated, 16 received renal transplants and 6 remained on CAPD. Active treatment was withdrawn in 1 child due to obliterative peritonitis. There were no deaths. One incident of peritonitis was documented per 11.6 patient treatment months. Recurring peritonitis lead to catheter replacement in 3 patients. Other problems encountered were catheter exit site infections, hernia formation and in one instance, hydrothorax. Peritonitis was more common in children under 2 years of age as was undernutrition, growth retardation and developmental delay. Home CAPD can be recommended as a viable first option treatment for childhood ESRF where suitable haemodialysis facilities are not easily accessible.

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CAPD作为儿童终末期肾功能衰竭主要治疗方法的疗效观察。
在本文发表之前的6年里,北爱尔兰所有出现终末期肾衰竭(ESRF)的儿童都选择性地开始进行持续动态腹膜透析(CAPD)。在此期间,22例患者接受治疗,16例接受肾移植,6例继续接受CAPD治疗。1例患儿因闭塞性腹膜炎退出积极治疗。没有人员死亡。每11.6个治疗月发生一例腹膜炎。复发性腹膜炎导致3例患者更换导尿管。其他遇到的问题是导管出口部位感染,疝形成,在一个实例中,胸腔积液。腹膜炎在2岁以下儿童中更为常见,营养不良、生长迟缓和发育迟缓也是如此。家庭CAPD可以推荐作为儿童ESRF可行的首选治疗方法,因为合适的血液透析设施不容易获得。
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