Age-variant and age-invariant rhythmicities in the cortical and hippocampal electrical activities of neonatal rats.

Chronobiologia Pub Date : 1992-07-01
M Dux, G Rubicsek, J Wolff, F Joó, G Benedek
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Abstract

The neocortical and hippocampal electrical activities were studied in 8, 15, 22, and 29-day-old rats. Segments of EEG recorded for 4 hours were analyzed by means of fast Fourier transformation. The sleep-wake activity stages were determined. The developments in the neocortical and hippocampal EEG activities were characterized by the gradual appearance of adult-like EEG waves and a shift towards higher frequencies in the theta wave range of the hippocampal electrical activity. The power value in the theta range, however, exhibited age-invariant rhythmicities with cycle lengths of about 9.5-11 and 16-22 min. The manifestation of such an age-invariant rhythm can be interpreted as an electrical manifestation of the rest-activity cycle originally described by KLEITMAN25.

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新生大鼠皮层和海马电活动的年龄变异和年龄不变节律性。
研究了8、15、22和29日龄大鼠大脑皮层和海马的电活动。采用快速傅立叶变换对记录的4 h脑电信号进行分析。确定了睡眠-觉醒活动阶段。新皮层和海马脑电活动的发展特点是逐渐出现成人样脑电波,海马脑电活动的θ波范围向更高频率转移。然而,theta范围内的功率值表现出年龄不变的节律性,周期长度约为9.5-11分钟和16-22分钟。这种年龄不变节律的表现可以解释为KLEITMAN25最初描述的休息-活动周期的电表现。
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