Bedside Percutaneous Tracheostomy for Patients with COVID 19 with Endotracheal Obstruction

G. Singh, R. Crawford, J. Cunningham
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Abstract

Introduction-A significant number of intubated COVID-19 patients may develop worrisome hemorrhage related to trachea-bronchial mucosal and submucosal slough due to severe inflammation/necrosis related to COVID-19 pneumonia. The accumulation of debris in the endotracheal tube can progress to severe endotracheal tube obstruction ( ETO) necessitating high peak driving pressures with eventual loss of satisfactory ventilator volume delivery. Emergency endotracheal tube exchange under these circumstances can be an extremely high-risk undertaking both for the patient and caregivers. Method-Thirty mechanically ventilated COVID-19 patients deemed at high risk for ETO or who had already had a prior episodes of ETO were selected as candidates for bedside percutaneous tracheostomy. Those patients requiring high ventilator settings high ventilator ( i.e. FIO2 > 50 and PEEP more than 10 ) were also included in the study group. A disposable bronchoscope was utilized for direct visualization of appropriate tracheal puncture, guidewire passage, and final positioning of the tracheal tube. Results-All patients, including those individuals on high ventilator support attained the primary outcome of successful percutaneous tracheostomy without serous adverse events. Minor adverse events, such as brief periods of oxygen desaturation, were observed in 3 patients. Conclusion-Bedside percutaneous tracheostomy is a safe therapeutic option for patients with high risk for ETO due to trachea-bronchial mucosal and submucosal slough. Consideration for early, elective intervention may be justified due to high risks associated with urgent/emergency endotracheal tube exchange.
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床边经皮气管造瘘术治疗新冠肺炎合并气管梗阻
大量经插管的COVID-19患者可能由于COVID-19肺炎相关的严重炎症/坏死而出现令人担忧的与气管-支气管粘膜和粘膜下脱落相关的出血。气管内管中碎片的积累可发展为严重的气管内管阻塞(ETO),需要高峰值驱动压力,最终失去令人满意的呼吸机容积输送。在这种情况下,紧急气管插管交换对患者和护理人员来说都是一项极其高风险的工作。方法:选择30例经机械通气的新型冠状病毒肺炎ETO高危患者或既往有ETO发作的患者作为床边经皮气管切开术的候选患者。那些需要高呼吸机设置的患者高呼吸机(即FIO2 >50例、PEEP≥10例也纳入研究组。使用一次性支气管镜直接观察合适的气管穿刺、导丝通道和气管管的最终定位。结果:所有患者,包括那些使用高呼吸机支持的患者,均达到了经皮气管切开术成功的主要结局,无严重不良事件。在3例患者中观察到轻微的不良事件,如短暂的氧饱和度下降。结论:床边经皮气管造瘘术对于气管支气管黏膜及粘膜下脱落的ETO高危患者是一种安全的治疗选择。考虑早期选择性干预可能是合理的,因为与紧急/紧急气管插管交换相关的高风险。
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