[Protective effect of sho-saiko-to (TJ 9) in experimental liver injury].

Ceskoslovenska farmacie Pub Date : 1992-10-01
V Eybl, D Caisová, J Koutenský, D Waitzová
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Abstract

Experiments carried out on male mice (ICR) demonstrated a protective effect of premedication with the preparation Sho-Saiko-To (TJ 9, Tsumura and Comp.) against the hepatotoxic effects of CCl4 and T1-acetate, which were manifested by increased peroxidation of lipids and increased depletion of reduced glutathion in liver homogenates.

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[sho-saiko-to (tj9)对实验性肝损伤的保护作用]。
在雄性小鼠(ICR)上进行的实验表明,用shoo - saiko - to制剂(tj9, Tsumura和Comp.)预用药对CCl4和t1 -醋酸酯的肝毒性作用具有保护作用,其表现为肝匀浆中脂质过氧化增加和还原型谷胱甘肽消耗增加。
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