[Effects of irradiation on fatty acid structure of membrane lipids of the sarcoplasmic reticulum].

Radiobiologiia Pub Date : 1992-11-01
Iu V Stepanov, V M Voĭtsitskiĭ, T D Preobrazhenskaia, I V Mel'nichuk, N E Kucherenko
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Abstract

It has been shown that single local X-irradiation (0.21 C/kg) of the rabbit hind limb in the early period of acute radiation injury (1 and 14 h) causes a decrease in saturation of sarcoplasmic reticulum membrane lipids. It is mainly connected with a decreased saturation of the total fraction of phosphatidyl serine, phosphatidyl inositol and phosphatidyl choline. The above changes can increase permeability of the sarcoplasmic reticulum membranes for Ca(2+)-ion after X-irradiation.

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[辐照对肌浆网膜脂脂肪酸结构的影响]。
结果表明,兔后肢急性辐射损伤早期(1和14 h)单次局部x射线照射(0.21 C/kg)可引起肌浆网膜脂饱和度降低。这主要与磷脂酰丝氨酸、磷脂酰肌醇和磷脂酰胆碱总分数饱和度降低有关。上述变化可增加x射线照射后肌浆网膜对Ca(2+)离子的通透性。
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