GEANT4 & GAMOS — A particle implementation of high energy simulation toolkit to oncology therapy

Sonali Sinha Bhatnagar, S. Sirisha
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引用次数: 2

Abstract

Monte-Carlo simulation is an essential tool that assists in the design of new medical imaging devices; optimize the treatment planning in dose estimation to control tumors in oncology therapy. Geant4 and GAMOS (Geant4 based Application for Medicine Oriented Simulations) implements the optimized radiotherapy external beam application, the propagation through an accelerator geometry and the calculation of the dose in voxel phantoms. This paper gives an overview of the physical processes involved along with detailed description of the design and implementation to medical physics in Geant4 and GAMOS toolkits. We have calculated the dose deposition of a passive proton beam of 60 to 240 MeV in a human phantom geometry. The resulting Bragg peak, range, penumbra width has been calculated and verified with results of other groups. The applications of these systems in fields of nuclear fragmentation for carbon ion therapy, nuclear imaging and hadrontherapy for in vivo dose monitoring are also discussed.
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GEANT4 & GAMOS -肿瘤治疗高能模拟工具包的粒子实现
蒙特卡罗模拟是帮助设计新的医学成像设备的重要工具;在肿瘤治疗中,通过剂量估算优化治疗计划,控制肿瘤。Geant4和GAMOS(基于Geant4的医学模拟应用程序)实现了优化的放射治疗外束应用,通过加速器几何形状的传播和体素幻象中剂量的计算。本文概述了所涉及的物理过程,并详细描述了Geant4和GAMOS工具包中医学物理的设计和实现。我们已经计算了60至240兆电子伏特的被动质子束在人体幻影几何中的剂量沉积。计算了所得的布拉格峰、范围、半影宽度,并与其他组的结果进行了验证。并讨论了这些系统在碳离子治疗的核碎裂、核成像和体内剂量监测的强子治疗等领域的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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