Evaluation of variation in dimensions of sella turcica in patients with unilateral cleft lip and palate as compared to Class I controls

Himija Karia, S. Shrivastav, A. Karia
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Abstract

The cleft of the lip and palate is the most common congenital anomaly affecting the cranio-facial region [1,2]. The etiology of CLP is said to be multi-factorial having both genetic and environmental causes. Clefts may be localized defects or may be associated with widespread structural changes in other parts of the skull [3]. Several studies have shown that the growth and displacement of the maxilla is directly linked to the growth and angulation of the cranial base [4-6]. Hence it may be assumed that any anomaly in the cranial base may have impact on the growth as well as spatial position of the naso-maxillary complex.
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评价单侧唇腭裂患者与I类对照患者蝶鞍尺寸的变化
唇腭裂是影响颅面区最常见的先天性畸形[1,2]。CLP的病因据说是多因素的,有遗传和环境原因。裂口可能是局部缺陷,也可能与颅骨其他部位广泛的结构改变有关[3]。多项研究表明,上颌骨的生长和位移与颅底的生长和成角直接相关[4-6]。因此,可以认为颅底的任何异常都可能对鼻颌复合体的生长和空间位置产生影响。
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