A Reliable Algorithm Based on Combination of EMG, ECG and EEG Signals for Sleep Apnea Detection : (A Reliable Algorithm for Sleep Apnea Detection)

M. K. Moridani, Mahdyar Heydar, Seyed Sina Jabbari Behnam
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引用次数: 15

Abstract

Sleep Apnea Syndrome is one of the most common and dangerous causes of sleep disorder that the suspected patients are tested (examined) by recording various types of vital signals during sleep using polysomnography (PSG). Since human body rhythms have a chaotic and non-linear behavior, the nonlinear analysis of body parameters provides the researchers with valuable information about body behavior during the disease and its comparison with the normal state for a more accurate examination of the diseases. The purpose of this is to diagnose apnea events using linear and nonlinear analyses and combining the EMG, ECG and EEG signals in patients with Obstructive Sleep Apnea (OSA). The research data are obtained by the Physionet database including 25 subjects (21 males and 4 females). After performing the pre-processing phase to remove the noise related to EMG, ECG, EEG and artifact signals based on the corresponding algorithms, the healthy and apnea sleep ranges are separated from one another. Linear and nonlinear analyses in MATLAB environment are performed on signals and conditions which are evaluated in healthy sleep and during sleep apnea at different stages of sleep in patients with OSA by multilayer perceptron classifier. The best result of the proposed algorithm obtained by combining the signals and the specificity, sensitivity and accuracy values are 96.87 ± 1.78, 97.14 ± 2.24 and 98.09 ± 2.15 respectively. The results show that the proposed algorithm can help doctors and nurses as a diagnostic tool with more accuracy than similar techniques.
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一种基于肌电、心电和脑电信号联合检测睡眠呼吸暂停的可靠算法(一种可靠的睡眠呼吸暂停检测算法)
睡眠呼吸暂停综合征是睡眠障碍最常见和最危险的原因之一,疑似患者在睡眠中使用多导睡眠图(PSG)记录各种生命信号进行测试(检查)。由于人体节律具有混沌和非线性的行为,对身体参数的非线性分析为研究人员提供了有关疾病期间身体行为及其与正常状态比较的有价值的信息,以便更准确地检查疾病。本研究的目的是通过线性和非线性分析,结合阻塞性睡眠呼吸暂停(OSA)患者的肌电、心电和脑电图信号来诊断呼吸暂停事件。研究数据来自Physionet数据库,共25名受试者(男21名,女4名)。根据相应算法对肌电、心电、脑电图及伪信号进行预处理,去除相关噪声后,分离出健康睡眠范围和呼吸暂停睡眠范围。利用多层感知器分类器在MATLAB环境下对OSA患者健康睡眠和不同睡眠阶段睡眠呼吸暂停时评估的信号和条件进行线性和非线性分析。结合信号得到的最佳结果为特异性、灵敏度和准确度分别为96.87±1.78、97.14±2.24和98.09±2.15。结果表明,该算法可以帮助医生和护士作为诊断工具,比同类技术更准确。
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