[Subpopulation state of T and B lymphocytes in hemolytic-uremic syndrome in children].

Pediatriia Pub Date : 1992-01-01
L T Tebloeva, O P Riabchikov, G N Surkova
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Abstract

A study was made of the quantitative characteristics of T and B lymphocytes and of their subpopulations (A-RFC; E37-RFC; auto-RFC; EAC-RFC; Ig(+)-cells) as well as of 0-lymphocytes in the peripheral blood of 20 children aged 6 to 24 months with different clinical stages of the hemolytic-uremic syndrome (oligoanuria, diuresis onset, polyuria, clinical improvement). It is concluded that all the stages of the disease are characterized by the deficiency of certain subpopulations of T cells (especially A-RFC, E37-RFC), B lymphocytes, and 0-cells. By the moment of the clinical improvement, the cellular characteristics of the immune status do not return to normal.

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[儿童溶血性尿毒症综合征患者T淋巴细胞和B淋巴细胞亚群状态]。
研究了T淋巴细胞和B淋巴细胞及其亚群(A- rfc;E37-RFC;auto-RFC;EAC-RFC;20例6 ~ 24月龄溶血性尿毒症综合征不同临床分期(少尿、利尿起病、多尿、临床好转)患儿外周血Ig(+)-细胞及0淋巴细胞的变化。结论:该疾病的所有阶段都以T细胞(特别是A-RFC、E37-RFC)、B淋巴细胞和0细胞的某些亚群缺乏为特征。到临床改善的那一刻,免疫状态的细胞特征并没有恢复正常。
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