Putri Nurhayati, Achmad Mujahidin Irham, I. G. B. Pramana, Herpan Syafii Harahap
{"title":"HBA1C SEBAGAI KANDIDAT BIOMARKER UNTUK PREDIKSI PROGESIVITAS GANGGUAN KOGNITIF TERKAIT DIABETES MELITUS TIPE 2","authors":"Putri Nurhayati, Achmad Mujahidin Irham, I. G. B. Pramana, Herpan Syafii Harahap","doi":"10.29303/jku.v11i1.517","DOIUrl":null,"url":null,"abstract":"Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia which underlie its complications, including cognitive impairment. T2dm-associated cognitive impairment is generally characterized by the decrease in at least one cognitive domain. However, its progression can be slowed by appropriate blood glucose control. Hb1Ac is a candidate of appropriate biomarker in predicting the progression of T2DM-associated cognitive impairment. This is based on several important characteristics it has, including a good blood glucose index, low daily biological variability, relatively unaffected by stress conditions, and unaffected by variations due to loading the amount of glucose.","PeriodicalId":135675,"journal":{"name":"Unram Medical Journal","volume":"32 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Unram Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29303/jku.v11i1.517","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia which underlie its complications, including cognitive impairment. T2dm-associated cognitive impairment is generally characterized by the decrease in at least one cognitive domain. However, its progression can be slowed by appropriate blood glucose control. Hb1Ac is a candidate of appropriate biomarker in predicting the progression of T2DM-associated cognitive impairment. This is based on several important characteristics it has, including a good blood glucose index, low daily biological variability, relatively unaffected by stress conditions, and unaffected by variations due to loading the amount of glucose.