Case Report of Successful Symptomatic Management of Elderly Patient with Very High-Risk MDS-Transformed AML

Hakobyan Y
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Abstract

American Society of Hematology (ASH) recommends antileukemic therapy over best supportive care for older adults with acute myeloid leukemia (AML) [1]. According to the SEER database from 2010 to 2017, the 5-year overall survival (OS) in individuals with AML diagnosis over 70 years of age was around 5% [2]. We describe a case of nearly one-year survival in an elderly patient with a very high-risk myelodysplastic syndrome (MDS) that later transformed into AML with supportive therapy only.
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高龄高危mds转化型急性髓系白血病症状管理成功病例报告
美国血液学会(ASH)推荐抗白血病治疗优于老年急性髓性白血病(AML)[1]的最佳支持治疗。根据2010年至2017年的SEER数据库,70岁以上AML患者的5年总生存率(OS)约为5%。我们描述了一位患有高危骨髓增生异常综合征(MDS)的老年患者,该患者在仅接受支持治疗后转变为AML,患者存活近一年。
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