[Prevalence of hepatitis B in the focus of HIV infection].

Pediatriia Pub Date : 1992-01-01
V F Uchaĭkin, B S Kaganov, T P Moleva, N V Sokolova, N B Sharaeva, V A Konev, A N Stepanov
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Abstract

Highly sensitive up-to-date research methods (enzyme immunoassay) for HbsAg and antibodies against HBsAg and HBcAg were employed to examine 565 adults and children living in the Kalmuck++ ASSR (Elista and adjacent regions), where in 1988-1989 cases of HIV-infection were recorded. Markers of HBV-infection were detected with a high enough frequency in the control group of children (15.2%). The prevalence of the infection in the adult population was at an intermediate level (38.9%). The high infectivity with HBV-infection was recorded among children who had been hospitalized before (for different diseases including chronic ones), among women who had undergone laboratory studies because of the diagnosis of HIV-infection in their children; among adult patients suffering from tuberculosis of morons from a closed boarding school. The highest frequency of HBV-infection marker demonstration was found in HIV-infected children (70%). The data obtained point to the necessity of vaccination against viral hepatitis B in risk groups (children and adults) and in the newborn as well as of raising the efficacy of preventing measures against infections transmitted via blood.

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[艾滋病毒感染焦点中的乙型肝炎患病率]。
采用高灵敏度的最新研究方法(酶免疫分析法)检测HbsAg和针对HbsAg和HBcAg的抗体,对Kalmuck++ ASSR (Elista及邻近地区)的565名成人和儿童进行了检查,记录了1988-1989年艾滋病毒感染病例。对照组儿童检测到hbv感染标志物的频率足够高(15.2%)。成人感染率处于中等水平(38.9%)。在以前住院的儿童(因不同的疾病,包括慢性病)中,在因其子女被诊断感染艾滋病毒而接受实验室检查的妇女中,记录了乙型肝炎病毒感染的高传染性;在一所关闭的寄宿学校的患肺结核的白痴的成年病人中。hiv感染儿童中出现hbv感染标记物的频率最高(70%)。所获得的数据表明,有必要在危险人群(儿童和成人)和新生儿中接种乙型病毒性肝炎疫苗,并提高预防经血液传播感染措施的效力。
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