Sainal Edi Kamal, Suprapto Prayitno, Syaibatul Hamdi
{"title":"Antipyretic Effectiveness Test from Dragon (Pyrosia piloselloides) (L) M. G. Price) Leaves Extract in Male Marmutes (Cavia Procellus)","authors":"Sainal Edi Kamal, Suprapto Prayitno, Syaibatul Hamdi","doi":"10.36060/jfs.v7i1.77","DOIUrl":null,"url":null,"abstract":"This study aims to determine Effectiveness Of Dragon Scale Leaves (Pyrrosia piloselloides (L.) M. G. Price) As An Antipyretic In Male Marmut (Cavia porcellus) induced with 5% peptone. This study used 15 male guinea pigs which were divided into V groups. roup I was given negative control (Na. CMC 1% w/v), groups II, III and IV were given dragon scales leaf extract at a dose of 250 mg/kg, 500 mg/kg, and 750 mg/kg and group V was given a positive control. (Paracetamol). previously induced with 5% peptone subcutan. measurements of body temperature rectally were carried out every 30 minutes, survived 4 hours. The results showed that the administration of dragon scales leaf extract at a dose of 250 mg/kg, 500 mg/kg, and 750 mg/kg of body weight gave an antipyretic effect against male guinea pigs and the most optimal effect is obtained at a dose of 750 mg/kgBW which is 129,05% compared to paracetamol which is 146,19%.","PeriodicalId":351011,"journal":{"name":"Jurnal Farmasi Sandi Karsa","volume":"123 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-04-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jurnal Farmasi Sandi Karsa","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36060/jfs.v7i1.77","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
This study aims to determine Effectiveness Of Dragon Scale Leaves (Pyrrosia piloselloides (L.) M. G. Price) As An Antipyretic In Male Marmut (Cavia porcellus) induced with 5% peptone. This study used 15 male guinea pigs which were divided into V groups. roup I was given negative control (Na. CMC 1% w/v), groups II, III and IV were given dragon scales leaf extract at a dose of 250 mg/kg, 500 mg/kg, and 750 mg/kg and group V was given a positive control. (Paracetamol). previously induced with 5% peptone subcutan. measurements of body temperature rectally were carried out every 30 minutes, survived 4 hours. The results showed that the administration of dragon scales leaf extract at a dose of 250 mg/kg, 500 mg/kg, and 750 mg/kg of body weight gave an antipyretic effect against male guinea pigs and the most optimal effect is obtained at a dose of 750 mg/kgBW which is 129,05% compared to paracetamol which is 146,19%.