A review on role of autopsy in the diagnosis of sudden arrhythmic deaths

Prashanth Mada, Pragnesh B. Parmar, Y. S, Divya Reddy Pannala
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Abstract

Sudden death (SD) is described as “death within 24 hours from the earliest manifestation, without any proof of violence and with no pre-existing disease, where no cause of death can be identified clinically”. In about 5%–10% of cases of sudden cardiac death (SCD), no underlying heart disease can be found at autopsy. Mostly these are the arrhythmic SCD and have a morphologically normal heart. There is a scope for uncertainty among relatives and/or investigating authorities regarding the cause & manner of death specifically in unattended sudden cardiac death. The postmortem examination must include detailed history or clinically relevant information of the deceased, his/her family members, macroscopic, microscopic, toxicological & molecular examination.
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尸检在猝死性心律失常死亡诊断中的作用
猝死被描述为"在最早出现症状后24小时内死亡,无任何暴力行为证据,没有先前存在的疾病,且无法在临床上确定死亡原因"。在大约5%-10%的心源性猝死(SCD)病例中,尸检时没有发现潜在的心脏疾病。这些大多是心律失常的SCD,心脏形态正常。亲属和/或调查当局对死因和死亡方式存在不确定性,特别是在无人照料的心源性猝死中。尸检必须包括死者及其家属的详细病史或临床相关资料,以及肉眼、显微镜、毒理学和分子检查。
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