NEUROENERGETIC MAPPING: A NEW DIAGNOSTIC TOOL FOR PATHOPHYSIOLOGICAL CHANGES IN THE CENTRAL NERVOUS SYSTEM IN CHILDREN WITH DEVELOPMENTAL DISORDERS

Abstract

The possibilities and advantages of neuroenergy mapping (NEM) in the diagnosis of pathologies of the central nervous system (CNS) in 78 children with developmental disorders are described. The NEM evaluates the intensity of the patient's cerebral energy exchange by comparing levels of constant potentials (LCP) in various brain areas with reference values. Computer visualization of these deviations from the norm is helpful in suggesting the presence of gross pathologies in the CNS. Its simplicity and convenience make NEM a tool applicable for examining children with severe and complex negative behavior, which sets it apart from other modern, instrumental brain studies. At the same time, it can solve fundamentally important problems in diagnosing the medical causes of negative behaviors in children with developmental disabilities. In this study, the NEM first identified children with no dominant CNS pathologies (36 children or 46%), and then divided the remaining children into their main type of obvious neurological pathologies (42 / 54%): • liquorodynamic disorders (24 / 31%) ; • cortical overexcitation (9 / 12%); • cortical ischemia (6 / 7%); • rare combinations of pathologies of the bone, endocrine, and nervous systems (3 / 4%). Classification of patients into groups of disorders, thanks to NEM data, allowed clinicians: • to develop and implement protocols for "point-based" follow-up research, • to suggest successful therapeutic strategies based on the final diagnosis, • to correct pharmacological interventions. Legitimate therapeutic and pharmacological interventions led to the stabilization and improvement of patients' conditions, up to and including the disappearance of negative behavior. The approach described in this article is of great importance for children with autism and other developmental disorders. When prescribing medications for these children, many doctors focus on diagnostic criteria such as negative and antisocial behavior (in accordance with official guidelines). However, the causes of negative behavior shown by NEM (for example, brain overexcitation versus cortical ischemia) are quite different, as are subsequent treatment protocols. We recommend that doctors who work with children with similar diagnoses, before prescribing neuroleptics and other medications, pay attention to possible medical causes of negative behavior. Ключевые слова: аутизм, гипоксия мозга, корковая ишемия, ликвородинамические нарушения, нарушения развития, нарушения центрального кровообращения, нейролептики, нейроэнергокартирование, РАС, СДВГ, эпилепсия, эписиндром. No 1 (74) январь, 2021 г.