A hybrid systems approach to integration of medical models

W. Kohn, J. James, A. Nerode, N. DeClaris
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引用次数: 6

Abstract

The authors discuss a fundamental problem in the provision of quality care at acceptable, society-wide costs: The integration of what is now a dichotomy in medical models. The dichotomy is one between phenomenological models of high-level decisions and evolution models of low-level dynamics. The dominant modeling concepts are based traditionally on (a) "homeostasis" and, (b) "physical dynamics"-such as those encountered in pharmacology, quantitative pathophysiology, and immunology. The authors introduce a novel idea of the hybrid system state which is used to provide a basis for integration of medical models.<>
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医学模型整合的混合系统方法
作者讨论了一个基本问题,在提供高质量的护理在可接受的,全社会的成本:什么是现在的二分法在医学模式的整合。这种二分法是高级决策的现象学模型和低级动力学的进化模型之间的二分法。主要的建模概念传统上基于(a)"体内平衡"及(b)“物理动力学”——比如在药理学、定量病理生理学和免疫学中遇到的那些。作者引入了一种新的混合系统状态思想,为医学模型的集成提供了基础。
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