A kardiovaszkuláris kockázat csökkentése 1-es típusú diabetes mellitusban, felnőttkorban

Abstract

Summary: In the past decades, the mortality of type 1 diabetes mellitus (T1DM) has greatly improved, according to the Swedish database the mortality decreased with 29%. Still there is 2-8-fold higher mortality rate in T1DM compared to the general population, causing an average of 12-year lower life expectancy in a 20- year-old individual. Recent studies suggest that earlier start of the disease is associated with higher mortality risk regardless of disease duration. The leading cause of death is cardiovascular mortality. Early complex cardiovascular risk reduction is an important aspect of the management of patient with T1DM. Its components are the good glycaemic control at the lowest possible incidence of hypoglycaemia, healthy lifestyle, regular exercise, avoidance of obesity and smoking, as well as treating other medically manageable risk factors (such as blood pressure, LDL-cholesterol and albuminuria) to target values. We summarize the available options of cardiovascular prevention in type 1 diabetes mellitus based on national and international guidelines and emphasize the importance of risk reduction among the young patients with T1DM.