[Neurosurgical aspects of urologic metastases].

G Miserocchi, L Bello, R Campanella, M Caroli, E Capricci, R Villani
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Abstract

Metastases in the central nervous system (C.N.S.) from urological tumors can be spinal or craniocerebral. The experience of 30 patients with spinal and craniocerebral metastases from urological tumors admitted to Neurosurgical Clinic of the University of Milan, is reported. They were 7.5% of the all number of metastases admitted at the Neurosurgical Department, during the same period. The brain metastases constitute 10% of brain metastases diagnosed in this period. Only patients with solitary (to CT scan and NMR) metastasis, and with a general prognosis that allow to an adequate and useful period of survival, are submitted to surgical treatment. 23 patients (76.6%) are surgical treated. The mean survival from the discovery of the C.N.S. metastases was 9 months (9.4 months among surgically treated patients and 7.8 months among those were not operated). Surgical mortality was 13%. Out of patients with survival until 5 months, patients submitted to surgical treatment showed a better quality of life. Our results allow us to affirm that in selected patients surgical removal of solitary metastases, could improve the quality of survival, but is not able to prolong substantially the period of survival.

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[神经外科方面的泌尿系统转移]。
泌尿系统肿瘤在中枢神经系统的转移可以是脊柱或颅脑。报告了米兰大学神经外科诊所收治的30例泌尿外科肿瘤脊柱和颅脑转移患者的经验。在同一时期,他们占神经外科收治的所有转移病例的7.5%。脑转移占这一时期确诊的脑转移瘤的10%。只有孤立(CT扫描和核磁共振)转移的患者,以及一般预后允许足够和有用的生存期的患者,才接受手术治疗。手术治疗23例(76.6%)。发现中枢神经系统转移后的平均生存期为9个月(手术患者为9.4个月,未手术患者为7.8个月)。手术死亡率为13%。在存活至5个月的患者中,接受手术治疗的患者表现出较好的生活质量。我们的结果使我们确认,在选定的患者中,手术切除孤立转移瘤可以提高生存质量,但不能显著延长生存期。
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