Staged Revision of Infected Hip Arthroplasty Using an Antibiotics-Loaded Intra-Articular Cement Spacer with Retention of the Stem

Y. Sung, Jong-Seok Oh
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引用次数: 3

Abstract

Purpose: When the femoral stem was well fixed in patients with a deep prosthetic hip infection, the authors performed a two-stage revision procedure using antibiotic-loaded cement spacers (ALCS) without removal of the stem, and the efficacy of this treatment was assessed. Materials and Methods: For 12 cases of infected hip arthroplasties, a two-stage procedure was performed, and the patients were followed up for over 2 years. After the acetabular component and head was removed, debridement was done. The molded ALCS was inserted. Revision was then performed after eradication of the infection. The results were analyzed, including the changes in the clinical manifestation, the radiologic findings, the laboratory results, the functional score and the complications. Results: Of all 12 cases, the two-stage revision arthroplasty using an ALCS with retention of the stem was performed in 11 cases (92%), on an average of 66 days (range: 40~152 days). In the 11 revised cases, there was no evidence of recurrence of infection. In the 11 cases, the mean Harris hip score improved from 40.1 points preoperatively to 91.8 points at last the follow-up. The mean WOMAC score improved from 41.8 points preoperatively to 81 points at the last follow-up. The mean Harris hip score was 85.3 points and the WOMAC score was 72.4 points during the ALCS insertion- period. Conclusion: For the case of a perioprosthetic hip infection with a well-fixed femoral stem, two-staged revision using an ALCS without stem removal could be an alternative method in terms of effective infection control and preservation of the joint function.
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使用含有抗生素的关节内水泥间隔器保留假体的感染髋关节置换术的分期翻修
目的:当深度人工髋关节感染患者的股骨柄固定良好时,作者使用抗生素负载的水泥间隔器(ALCS)进行了两阶段的翻修手术,而不移除股骨柄,并评估了这种治疗的疗效。材料与方法:对12例感染性髋关节置换术患者进行两期手术,随访2年以上。在髋臼部件和头被移除后,进行清创。插入成型的ALCS。然后在感染根除后进行翻修。分析两组患者的临床表现、影像学表现、实验室检查结果、功能评分及并发症的变化。结果:在所有12例病例中,11例(92%)采用ALCS进行了两期翻修关节置换术,平均66天(范围:40~152天)。在11例修订病例中,没有感染复发的证据。11例患者Harris髋关节平均评分由术前40.1分提高到随访时的91.8分。平均WOMAC评分从术前的41.8分提高到最后一次随访时的81分。在ALCS插入期间,Harris髋关节平均评分为85.3分,WOMAC评分为72.4分。结论:对于固定良好的股骨干髋关节周围感染病例,使用ALCS而不切除股骨干的两阶段翻修可能是有效控制感染和保存关节功能的替代方法。
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