Hyperprolactinemia following traumatic myelopathy

A. Esan, Jokotade Adeleye, Abimbola Olukayode Lawal, Oluwakemi A. Badejo
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Abstract

Prolactin, an anterior pituitary gland hormone, is necessary for breast development in pregnancy and initiation of lactation. Prolactinomas constitute a pathological cause of elevated serum prolactin levels and are the most common type of pituitary adenomas. Excess prolactin could result from physiological causes that include pregnancy, lactation, sleep, and coitus. The usual presentation of hyperprolactinemia is galactorrhea. There are reports of elevated prolactin levels following other pathological causes such as chest wall lesions, chest wall trauma, and medications. We report the rare association of hyperprolactinemia with traumatic injury to the spinal cord in a Nigerian patient, and a brief review of the relevant literature.
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外伤性脊髓病并发高泌乳素血症
催乳素是一种垂体前叶激素,对妊娠期乳房发育和泌乳起始是必需的。催乳素瘤是引起血清催乳素水平升高的病理原因,是垂体腺瘤中最常见的类型。过多的催乳素可能是由生理原因引起的,包括怀孕、哺乳、睡眠和性交。高催乳素血症通常表现为溢乳。有报道称,由于其他病理原因,如胸壁病变、胸壁创伤和药物治疗,催乳素水平升高。我们报告高催乳素血症与创伤性脊髓损伤在尼日利亚患者罕见的关联,并简要回顾相关文献。
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