Removal of Oxytetracycline in Pharmaceutical Effluents by Using Synthetic Adsorbents

Abstract

Simple, accurate, fast, and economical method for removal of OTC in Pharma wastewater has been developed. The procedure is based on the adsorption mechanism which leads to the spectrophotometry. Bentone -34 clay is used as an adsorbent for removal of OTC. 0.1 N HCl was used as a mobile phase. The elute was determined spectroscopically, with a Cecil CE 2041 UV/VIS spectro -photometer, in a 1-cm Cuvette cell at wavelength range 190-1100 nm, with resolution 0.5 nm. The linear calibration curve was established in the concentration range 0.214-1.070 mg/mL of OTC. From the analyzed data the following results for parameters were obtained linearity correlation R 2 > 0.9984), accuracy (Recovery = 91-98%), sensitivity (LOD = 42.3 mg/mL; LOQ = 48.3 mg/mL), and precision (RSD ≥ 2.0%) in the respective linear concentration ranges. The method is successfully applied for the removal of OTC as the tested sample improves ICH parameters like accuracy, sensitivity, precision. been previously investigated. The present work involved a study of the adsorption process of the oxytetracycline (OTC) from aqueous solution by Bentone-34 as adsorbent material. (Bentone 34 is an organic derivative of a special smectite. It is manufactured by chemically modifying naturally occurring clays like bentonite) [10, 11]. adsorption and low-cost develop fast, and economical method for removal of in Pharma deter mination were estimated from the standard deviation of the response and the slope, based on the data of the calibration curve. The limit of detection (LOD) and limit of quantification (LOQ) were found to be 42.3 mg/mL and 48.3 mg/ml. The LOD and LOQ showed that this method is sensitive for OTC determination. precision, sensitivity. The results of the present study are indicative of Bentone-34 as a new alternative low cost adsorbent for removing the oxytetracycline from Pharma wastewater.