Prediction of Breast Cancer Risk Factors Using Neural Network Analytics: an Empirical Study

Ahed J. Alkhatib, Shadi M. Alkhatib
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Abstract

Breast cancer is the most prevalent cancer affecting women. Identifying breast cancer risk factors are crucially to be established. The main objectives of the present study were to identify the predictors of breast cancer risk factors and their relative importance using neural network analysis. The present study depended on neural network analysis of data posted on [1]. The dataset is about predictors of breast cancer. There were 9 covariates included and one dependent variable, output (no disease (1), or disease (2)). The dataset was composed of 116 cases. The category of no disease comprised 79 (68.1%) cases, whereas the disease category included 37 cases (31.9%). Architecture model was built with some characteristics such as training part: gross entropy error was 23.7884, the percent of incorrect predictions was 10.1%. Stopping rule used was 1 consecutive step(s) with no decrease in error. For testing part, gross entropy error was 14,327, the percent of incorrect predictions was 13.5%. The relative importance of breast cancer was in the following order: glucose, resistin, BMI, age, leptin, adiponectin, MCP-1, insulin, and HOMA. Taken together, neural network analysis is an efficient tool to predict breast cancer risk factors.
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用神经网络分析预测乳腺癌危险因素的实证研究
乳腺癌是影响女性的最普遍的癌症。确定乳腺癌的危险因素至关重要。本研究的主要目的是利用神经网络分析确定乳腺癌危险因素的预测因素及其相对重要性。本研究依赖于对发表在[1]上的数据进行神经网络分析。这个数据集是关于乳腺癌的预测因子。共纳入9个协变量和1个因变量,即输出(无疾病(1)或疾病(2))。该数据集由116个病例组成。无病类79例(68.1%),有病类37例(31.9%)。构建了具有训练部分等特征的体系结构模型:总熵误差为23.7884,预测错误率为10.1%。使用的停止规则是连续1步(s),误差没有减少。测试部分的总熵误差为14327,预测错误率为13.5%。乳腺癌的相对重要性依次为:葡萄糖、抵抗素、BMI、年龄、瘦素、脂联素、MCP-1、胰岛素和HOMA。综上所述,神经网络分析是预测乳腺癌危险因素的有效工具。
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