Post-vagotomy variations of gastric mucosal mast cells in the rat.

Journal of Experimental Pathology Pub Date : 1992-01-01
J L Marcos Rodríguez, J M Alcalde Escribano, A Brea Hernando, C Blanco García, L Buelta Carrillo, J F Val-Bernal
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Abstract

The effects of the vagus and its action on the mucosal mast cells (MMC) of the secretory portion of the rat stomach are analyzed by observing the consequences caused by subdiaphragmatic truncal vagotomy on the MMC in terms of cell count and degranulation over a period of four months. Observations showed a gradual decrease in the number of mast cells/mm2, an increase in the percentage of MMC in a state of degranulation, but the same number of degranulated cells/mm2. This suggests that the vagus controls both numerically and functionally the MMC population in the secretory portion of the rat stomach.

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迷走神经切开术后大鼠胃粘膜肥大细胞的变化。
通过观察4个月膈下截尾迷走神经对大鼠胃粘膜肥大细胞(MMC)细胞计数和脱颗粒的影响,分析了迷走神经对胃粘膜肥大细胞(MMC)的影响及其作用。观察显示肥大细胞数逐渐减少/mm2,脱颗粒状态的MMC百分比增加,但脱颗粒细胞数不变/mm2。这表明迷走神经在数量上和功能上控制了大鼠胃分泌部分的MMC种群。
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