COVID-19 and Children with Congenital Heart Disease: Pandemic Implication

M. Mamun, M. Hussain, R. Rima
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Abstract

While the global coronavirus crisis worsens, a surprising feature of the disease appears that children might be immune from the worst form of it. Studies suggest that COVID- 19 is more likely to infect older adult men, particularly those with comorbidities. There is only limited data detailing the effects of COVID-19 on the pediatric population. Patients with underlying cardiovascular comorbidities are at increased risk of morbidity and mortality from SARS-CoV-2 infection. Certain adult patients with congenital heart disease (ACHD) and with complex congenital heart disease can be considered as high risk for complications related to COVID-19 infection on the basis of decreased functional reserve. While no study on COVID-19 has been included paediatric patients with congenital heart disease, it stands to reason that patients with congenital heart disease can be considered at higher risk for complications from COVID-19. Given the increased risk for severe COVID-19 in adults with underlying cardiac disease, there is concern that patients with congenital heart disease (CHD) may likewise be at increased risk for severe infection, as they are known to have higher risk for complications with viral illnesses including respiratory syncytial virus and influenza. DS (Child) H J 2020; 36(2): 138-145
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COVID-19与先天性心脏病儿童:大流行意义
在全球冠状病毒危机恶化的同时,该疾病的一个令人惊讶的特征似乎是,儿童可能对最严重的冠状病毒免疫。研究表明,COVID- 19更有可能感染老年男性,特别是那些有合并症的男性。详细说明COVID-19对儿科人群影响的数据有限。伴有潜在心血管合并症的患者因SARS-CoV-2感染而发病和死亡的风险增加。部分成年先天性心脏病(ACHD)及复杂先天性心脏病患者,基于功能储备下降,可考虑为COVID-19感染相关并发症的高危人群。虽然没有关于COVID-19的研究纳入患有先天性心脏病的儿科患者,但有理由认为患有先天性心脏病的患者患COVID-19并发症的风险更高。鉴于患有潜在心脏病的成年人患严重COVID-19的风险增加,人们担心先天性心脏病(CHD)患者患严重感染的风险也可能增加,因为已知他们患病毒性疾病(包括呼吸道合胞病毒和流感)并发症的风险更高。DS(儿童)[J] 2020;36 (2): 138 - 145
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