Karius-ity and the Cat: Diagnosing Hepatosplenic Bartonella Using Next Generation DNA Sequencing and Imaging

Samuel H. Masur, A. Hayward, C. Sanders, D. Farmakiotis
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Abstract

Case Summary: A 23-year-old female with common variable immunodeficiency (CVID), presented with intermittent epigastric pain, which would eventually spread to her entire abdomen. She had night sweats, chills, and regular stools. She had been evaluated twice over the last two months for posterior cervical lymphadenopathy and similar abdominal symptoms, which were attributed to a possible EBV infection. Her exam was notable for diffuse abdominal tenderness, worse in the epigastric region, without rebound or guarding. Additionally, she had a non-tender fixed lymph node in the right posterior cervical chain. Her medical …
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Karius-ity和Cat:使用下一代DNA测序和成像诊断肝脾巴尔通体
病例总结:一名23岁女性,患有常见变异性免疫缺陷(CVID),表现为间歇性上腹部疼痛,最终扩散到整个腹部。她盗汗、发冷、经常大便。在过去的两个月里,她被检查了两次颈椎后淋巴结病变和类似的腹部症状,这些症状可能是EBV感染所致。检查发现弥漫性腹部压痛,上腹更严重,无反弹或守卫。此外,她在右侧颈后链有一个无压痛的固定淋巴结。她的医疗…
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