In response to Swamidas and Kirisits

S. van Dyk, K. Narayan
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Abstract

We were dismayed to read the short and unsatisfactory paragraph discussing the use of transabdominal ultrasound to guide brachytherapy for cervix cancer in an editorial from a country burdened with one‐fifth of all new cases of cervix cancer. We expected a more pragmatic approach from this region given the recognition of the disparity in resource and technology utilization between external beam treatment and brachytherapy in your environment. To say that ultrasound “will certainly play an important role in the future” implies ultrasound has no role in the present, this is both erroneous and mendacious reporting. Two clinical outcome studies using transabdominal ultrasound have been reported in the literature, neither of which were discussed in the editorial.[1,2] These reports have both shown how the use of low cost accessible transabdominal ultrasound can incorporate soft tissue imaging into a brachytherapy program and achieve similar survival rates and late effects as magnetic resonance imaging‐based three‐dimensional planning. It is possible to see the width, height, and thickness of the cervix using transabdominal ultrasound. One just has to turn the transducer through 90°. To caution against the use of ultrasound because technology is not as advanced as desired is extremely self‐limiting. It is not necessary to track the applicator in relation to the ultrasound scan set as the applicator itself acts as a fiducial and calibration device within the image. Transrectal ultrasound (TRUS) is limited by the short focal length (60 mm) and small field of view and while it may be a useful tool to assess cervix tumor width, there are no reports of its use in measuring cervix tumor height in locally advanced cancers. Tumor width, height, and thickness have not been measured with the applicator in situ with TRUS, nor has brachytherapy been planned using these images. At present, two‐dimensional transabdominal ultrasound images, which depict the applicator and anatomy, are used to verify applicator position by many departments around the world and used to guide planning in the two departments mentioned. These two departments have shown that use of transabdominal ultrasound significantly improved the dose distribution for target and OAR in comparison with conventional point X‐ray based planning. In a region where X‐ray based planning is the norm, resources are limited and patients are poor, it behooves us to explore accessible time and cost‐effective solutions and make image‐guided conformal brachytherapy possible for all.
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回应Swamidas和Kirisits
当我们在一篇社论中读到这篇关于使用经腹超声指导宫颈癌近距离治疗的短文时,我们感到沮丧,这篇社论来自一个占所有宫颈癌新病例五分之一的国家。考虑到在你们的环境中,外部光束治疗和近距离治疗在资源和技术利用上的差异,我们期望该地区采取更务实的方法。说超声波“在未来肯定会发挥重要作用”,意味着超声波在现在没有作用,这是错误的和虚假的报道。文献中已经报道了两项使用经腹超声的临床结果研究,但这两项研究都没有在社论中讨论。[1,2]这些报告都表明,使用低成本的经腹超声可以将软组织成像纳入近距离治疗方案,并获得与基于磁共振成像的三维计划相似的生存率和后期效果。使用经腹超声可以看到子宫颈的宽度、高度和厚度。只需要将传感器旋转90°。由于超声技术不像期望的那样先进而对其使用提出警告是极其自我限制的。由于涂敷器本身在图像中充当基准和校准装置,因此没有必要跟踪涂敷器与超声扫描集的关系。经直肠超声(TRUS)由于焦距短(60mm)和视野小而受到限制,虽然它可能是评估宫颈肿瘤宽度的有用工具,但尚无报道将其用于测量局部晚期癌症的宫颈肿瘤高度。肿瘤的宽度、高度和厚度尚未用TRUS原位涂敷器测量,也未计划使用这些图像进行近距离治疗。目前,二维经腹超声图像描绘了施药器和解剖结构,被世界各地的许多部门用于验证施药器的位置,并用于指导上述两个部门的计划。这两个科室的研究表明,与传统的基于X线点的计划相比,经腹超声的使用显著改善了靶和桨叶的剂量分布。在一个以X射线为基础的规划是常态的地区,资源有限,病人贫穷,我们有必要探索可获得的时间和成本效益的解决方案,使图像引导的适形近距离治疗成为可能。
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