In Vitro Fertilization

J. Zolton, R. Chattopadhyay, A. DeCherney
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Abstract

Assisted reproductive technology (ART) encompasses all procedures that manipulate the oocytes, sperm, and embryos outside of the body. Decades of research have allowed the field to emerge as a reliable and safe treatment for infertile men and women. Indications for in vitro fertilization (IVF) include tubal factor infertility, anovulation, male factor infertility, and decreased ovarian reserve. Treatment is not limited to the infertile population, as IVF with preimplantation genetic diagnosis also offers patients an opportunity to prevent transmission of a genetic condition for which they have been found to carry. The field of ART continues to rapidly evolve, as more knowledge is gained from studies reporting on ovarian stimulation protocols, reproductive techniques such as intracytoplasmic sperm injection, and blastocyst transfer. Techniques are aimed to improve live birth rates while ensuring the optimal health of children conceived using IVF. This review contains 8 figures, 5 tables and 63 references Key Words: assisted reproductive technology, blastocyst, decreased ovarian reserve, embryo transfer, gonadotropin-releasing hormone agonist, gonadotropin-releasing hormone antagonist, intracytoplasmic sperm injection, luteal phase support, ovarian hyperstimulation syndrome, vitrification
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体外受精
辅助生殖技术(ART)包括在体外操纵卵母细胞、精子和胚胎的所有程序。几十年的研究使该领域成为一种可靠和安全的治疗不育男性和女性的方法。体外受精(IVF)的适应症包括输卵管因素不育、无排卵、男性因素不育和卵巢储备减少。治疗并不局限于不育人群,因为植入前遗传学诊断的体外受精也为患者提供了一个机会,以防止他们已经发现携带的遗传疾病的传播。随着对卵巢刺激方案、生殖技术(如胞浆内单精子注射和囊胚移植)的研究报告获得更多知识,抗逆转录病毒治疗领域继续迅速发展。技术旨在提高活产率,同时确保使用体外受精怀孕的儿童的最佳健康。关键词:辅助生殖技术,囊胚,卵巢储备减少,胚胎移植,促性腺激素释放激素激动剂,促性腺激素释放激素拮抗剂,卵浆内单精子注射,黄体期支持,卵巢过度刺激综合征,玻璃化
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Normal Sexual Development and Puberty Pre-implantation Screening and Diagnosis Preterm Premature Rupture of Membranes Recurrent Urinary Tract Infections The Puerperium
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