Comparison of the clinical efficacy of two commercial fatty acid supplements (EfaVet and DVM Derm Caps), evening primrose oil, and cold water marine fish oil in the management of allergic pruritus in dogs: a double-blinded study.

The Cornell veterinarian Pub Date : 1992-07-01
D W Scott, W H Miller, G A Decker, J R Wellington
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Abstract

Twenty dogs with atopy or idiopathic pruritus were treated in a double-blinded clinical trial with computer-randomized and computer-generated sequences of 4 fatty acid-containing products: evening primrose oil, cold water marine fish oil, DVM Derm Caps, and EfaVet. Each dog received each product for a 2-week period. Five of 20 dogs (25%) had a good-to-excellent reduction in their level of pruritus with at least 1 of the products: evening primrose oil (2 dogs), DVM Derm Caps (1), EfaVet (1), DVM Derm Caps and cold water marine fish oil (1). Only 1 dog experienced a side effect (loose stools). Clinical response to fatty acid supplements appeared to be quite individualized, and independent of age, breed, sex, weight, duration of disease, specific diagnosis, or number of positive intradermal test reactions.

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比较两种商业脂肪酸补充剂(EfaVet和DVM Derm Caps)、月见草油和冷水海洋鱼油治疗狗过敏性瘙痒的临床疗效:一项双盲研究。
20只患有特应性或特发性瘙痒的狗在一项双盲临床试验中使用计算机随机和计算机生成的4种含脂肪酸产品序列:月见草油、冷水海洋鱼油、DVM Derm Caps和EfaVet。每只狗在两周内接受每种产品。20只狗中有5只(25%)的瘙痒程度在至少1种产品的帮助下得到了良好到优异的缓解:月见草油(2只狗)、DVM护肤帽(1只狗)、EfaVet(1只狗)、DVM护肤帽和冷水海洋鱼油(1只狗)。只有1只狗出现了副作用(稀便)。对脂肪酸补充剂的临床反应似乎是非常个性化的,与年龄、品种、性别、体重、疾病持续时间、特定诊断或皮内试验阳性反应的数量无关。
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