Studies of the effect of acemannan on retrovirus infections: clinical stabilization of feline leukemia virus-infected cats.

Molecular biotherapy Pub Date : 1991-03-01
M A Sheets, B A Unger, G F Giggleman, I R Tizard
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Abstract

Feline leukemia is a disease induced by an oncornavirus infection that inevitably causes clinically affected cats to die. It has been estimated that 40% of cats are dead within 4 weeks and 70% within 8 weeks of the onset of clinical symptoms. Acemannan is a complex carbohydrate with both immunostimulatory and direct antiviral properties. Administration of acemannan for 6 weeks intraperitoneally to clinically symptomatic cats significantly improved both the quality of life and the survival rate. Twelve weeks after initiation of treatment, 71% of treated cats were alive and in good health.

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阿赛曼南对逆转录病毒感染的影响研究:猫白血病病毒感染猫的临床稳定。
猫白血病是一种由冠状病毒感染引起的疾病,不可避免地导致临床感染的猫死亡。据估计,40%的猫在出现临床症状后4周内死亡,70%在8周内死亡。葡甘露聚糖是一种复杂的碳水化合物,具有免疫刺激和直接抗病毒特性。对有临床症状的猫腹腔注射阿西曼南6周,显著改善了猫的生活质量和生存率。在开始治疗12周后,71%的接受治疗的猫存活且健康状况良好。
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