Evaluation of Asthma Control in Patients with and without Sinonasal Polyps following Treatment with Biologic Agents

Prachi M. Patel, Chandala Chitguppi, MD, Alan Gandler, MD, Kira Murphy, MD, Tawfiq Khoury, MD, Stephanie Bork, CRNP, Pamela Monostra, PA, Elina Toskala, MD, PhD, Mindy Rabinowitz, MD, Marc Rosen, MD, Gurston Nyquist, MD, Jessica Most, MD
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Abstract

Conclusions: Patients with and without sinonasal polyps who begin biologic therapy are shown to have significant improvements in their ACT score at follow-up. In addition, patients with polyps are shown to have significantly better control of their asthma while on biologics than patients with no polyps. Comorbid CRSwNP may predict response to biologic therapy in those with severe asthma (SA).
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鼻窦息肉患者与非鼻窦息肉患者生物制剂治疗后哮喘控制的评价
结论:开始生物治疗的鼻窦息肉患者和非鼻窦息肉患者在随访时的ACT评分均有显著改善。此外,与没有息肉的患者相比,有息肉的患者在服用生物制剂时对哮喘的控制明显更好。合并症CRSwNP可以预测严重哮喘(SA)患者对生物治疗的反应。
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