Self-tracking Energy Transfer for Neural Stimulation in Untethered Mice

J. S. Ho, Y. Tanabe, S. Iyer, A. Christensen, L. Grosenick, K. Deisseroth, S. Delp, A. Poon
{"title":"Self-tracking Energy Transfer for Neural Stimulation in Untethered Mice","authors":"J. S. Ho, Y. Tanabe, S. Iyer, A. Christensen, L. Grosenick, K. Deisseroth, S. Delp, A. Poon","doi":"10.1103/PhysRevApplied.4.024001","DOIUrl":null,"url":null,"abstract":"Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and electrical microstimulation require tethers or large head-mounted devices that disrupt animal behavior. We report a method for wireless powering of small-scale implanted devices based on the strong localization of energy that occurs during resonant interaction between a radio-frequency cavity and intrinsic modes in mice. The system features self-tracking over a wide (16 cm diameter) operational area, and is used to demonstrate wireless activation of cortical neurons with miniaturized stimulators (10 mm$^{3}$, 20 mg) fully implanted under the skin.","PeriodicalId":298664,"journal":{"name":"arXiv: Neurons and Cognition","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2015-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"37","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"arXiv: Neurons and Cognition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1103/PhysRevApplied.4.024001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 37

Abstract

Optical or electrical stimulation of neural circuits in mice during natural behavior is an important paradigm for studying brain function. Conventional systems for optogenetics and electrical microstimulation require tethers or large head-mounted devices that disrupt animal behavior. We report a method for wireless powering of small-scale implanted devices based on the strong localization of energy that occurs during resonant interaction between a radio-frequency cavity and intrinsic modes in mice. The system features self-tracking over a wide (16 cm diameter) operational area, and is used to demonstrate wireless activation of cortical neurons with miniaturized stimulators (10 mm$^{3}$, 20 mg) fully implanted under the skin.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
非系绳小鼠神经刺激的自跟踪能量转移
在小鼠自然行为过程中对神经回路进行光或电刺激是研究脑功能的一个重要范例。传统的光遗传学和电微刺激系统需要绳索或大型头戴式设备来干扰动物的行为。我们报告了一种小型植入设备无线供电的方法,该方法基于在小鼠射频腔和固有模式之间的共振相互作用期间发生的强能量定位。该系统的特点是在一个宽(直径16厘米)的操作区域内进行自我跟踪,并用于演示使用完全植入皮肤下的小型化刺激器(10毫米$^{3}$,20毫克)对皮质神经元的无线激活。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Phase-amplitude coupling in neuronal oscillator networks Quality of internal representation shapes learning performance in feedback neural networks Generalisation of neuronal excitability allows for the identification of an excitability change parameter that links to an experimentally measurable value Short term memory by transient oscillatory dynamics in recurrent neural networks Predicting brain evoked response to external stimuli from temporal correlations of spontaneous activity
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1