Intravesical Prostatic Protrusion as A Predictor of Need for Surgical Therapy in Benign Prostatic Hyperplasia Patients

B. Eze
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Abstract

Intravesical prostatic protrusion (IPP) can predict disease progression and development of complications in benign prostatic hyperplasia (BPH). The aim was to determine if IPP at initial evaluation can predict need for surgical therapy in BPH patients. A retrospective study of BPH patients at ESUT Teaching Hospital, Enugu. Patients were involved in a previous prospective study in which they had abdominal ultrasonography measurement of IPP and prostate volume (TPV). IPP was measured in millimeter and divided into < 10 mm and ≥ 10 mm. The clinicians were blinded about the patients’ IPP while making decision for therapy. After at least a 24-month follow up period, biodata, IPP, TPV, IPSS and therapy given/recommended were retrieved and analyzed. The odds ratio of having/awaiting surgery at IPP cut-off of 10 millimeters was calculated. P < 0.05 was considered significant. One hundred patients’ records were reviewed. Forty-four patients (44%) were still on medical therapy, 20 (20%) were awaiting surgery and 36 (36%) had prostatectomy. Eight (19.05%) of 42 patients with IPP < 10 mm had or were recommended for surgical therapy while 48 (82.76%) of 58 patients with IPP ≥ 10 mm had or were recommended for surgical therapy (p=0.000). There was a statistically significant odd for surgical therapy when IPP at initial evaluation was ≥ 10mm (OR=20.40, 95% CI [7.30,57.04]). IPP at initial evaluation ≥ 10 mm is a significant predictor of needing surgical therapy in BPH patients.
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膀胱内前列腺突出作为良性前列腺增生患者需要手术治疗的预测因子
膀胱内前列腺突出(IPP)可以预测良性前列腺增生(BPH)的疾病进展和并发症的发生。目的是确定IPP在初始评估时是否可以预测前列腺增生患者是否需要手术治疗。埃努古ESUT教学医院BPH患者的回顾性研究。患者参与了先前的一项前瞻性研究,在该研究中,他们进行了腹部超声测量IPP和前列腺体积(TPV)。IPP以毫米为单位测量,分为< 10 mm和≥10 mm。临床医生在决定治疗方案时对患者的IPP不知情。在至少24个月的随访期后,检索并分析生物数据、IPP、TPV、IPSS和给予/推荐的治疗方法。计算在IPP截止值为10毫米时进行/等待手术的优势比。P < 0.05被认为是显著的。审查了100名患者的记录。44例(44%)患者仍在接受药物治疗,20例(20%)患者正在等待手术,36例(36%)患者已行前列腺切除术。42例IPP < 10 mm的患者中有8例(19.05%)已经或推荐手术治疗,58例IPP≥10 mm的患者中有48例(82.76%)已经或推荐手术治疗(p=0.000)。初始评估IPP≥10mm时,手术治疗的差异有统计学意义(OR=20.40, 95% CI[7.30,57.04])。初始评估IPP≥10 mm是BPH患者需要手术治疗的重要预测指标。
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