MHC Regulation Based Immune Formula Discovering Algorithm (IFDA)

Min Hu, Weiming Sun
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引用次数: 15

Abstract

After having analyzed the advantage and disadvantage of gene expression programming (GEP), this paper proposes an innovative immune formula discovering algorithm (IFDA), which is actually inspired by MHC (major histocompatibility complex) regulation principle of immune theory. In IFDA, the formula are mapped as tree structure and transformed into both constant and variation section of antibody with a depth- first mechanism while its fragment is encoded into the MHC. Using the feature of MHC regulation, IFDA provides a quick solution to discover the proper formula. Many benchmark data are used for verifying the performance of IFDA in which all results from experiments show that the IFDA can really provide better performance than GEP.
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基于MHC调控的免疫公式发现算法
在分析了基因表达编程(GEP)的优缺点后,本文提出了一种创新的免疫公式发现算法(IFDA),该算法实际上是受到免疫理论中MHC(主要组织相容性复合体)调节原理的启发。在IFDA中,该公式被映射为树状结构,并以深度优先的机制转化为抗体的恒定段和变异段,同时将其片段编码到MHC中。利用MHC调节的特点,IFDA提供了一个快速找到合适配方的解决方案。利用大量的基准数据验证了IFDA的性能,所有的实验结果都表明IFDA确实可以提供比GEP更好的性能。
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