Management of Surgical Site Infections in Spine Surgery: A Current Concept Review

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Abstract

Background: Surgical sites infections (SSIs) in spine surgeries represent one of the commonest hospital-acquired infections. SSIs refers to infection of surgical wound within 30 days of surgery or one year of implant usage. SSIs portend a huge disease burden with devastating consequences to the patient and the hospital facility with attendant physical and psychological trauma to the patient and it is associated with increase rate of morbidity and mortality. Objective: The aim of this review is to identify factors that predispose a spine patient to SSIs and to highlight the current preventive and management concepts. Methods: We carried out a comprehensive review of literatures, using key words such as surgical site infections, spine surgery, predisposing factors, prevention, diagnosis, treatment, outcomes on search engines of Google Scholar, Scopus and PUBMED. Eligible articles for the review included full length published articles in English which we have access to contents. Results: Twenty-five full length articles were found eligible for the review. In spite of improvement in spine care and surgery, SSIs continue be a source of great concern to the patients, surgeons and healthcare system of any nation. Gram positive organisms are more common than gram negative organisms. The risk factors for SSIs include patient- and surgeon - related factors. Albeit, there is no universally accepted protocol for the prevention and treatment of SSIs in spine surgery. The incidence of SSIs is on the increase worldwide with associated high risk of morbidity, overall decrease in the quality of life and sometimes mortality. The economic burdens of the management of SSI is huge and stressful for every nation. Treating SSIs after spine surgery is daunting as the choice between removing the implants for proper bacteria clearance and the risk of causing spinal instability is a hard nut to crack. Conclusions: Despite the improved surgical technique, protocol on asepsis and role of prophylactic antibiotics in clean spine surgeries, there are still substantial increase in the rate of SSIs. Therefore, prevention is more profitable than the hope of proper treatment.
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脊柱外科手术部位感染的处理:当前概念综述
背景:脊柱外科手术部位感染是最常见的医院获得性感染之一。ssi是指手术后30天内或种植体使用一年内发生的手术伤口感染。ssi预示着巨大的疾病负担,对患者和医院设施造成毁灭性后果,给患者带来生理和心理创伤,并与发病率和死亡率增加有关。目的:本综述的目的是确定脊柱患者易患ssi的因素,并强调当前的预防和管理概念。方法:以手术部位感染、脊柱外科、易感因素、预防、诊断、治疗、结局等为关键词,在谷歌Scholar、Scopus、PUBMED等搜索引擎上进行文献综述。符合审查条件的文章包括我们可以访问内容的完整长度的英文发表文章。结果:25篇全文文章符合审查条件。尽管脊柱护理和外科手术有所改善,但ssi仍然是任何国家患者,外科医生和医疗保健系统非常关注的问题。革兰氏阳性菌比革兰氏阴性菌更常见。ssi的危险因素包括患者和外科医生相关的因素。尽管如此,对于脊柱外科手术中ssi的预防和治疗尚无普遍接受的方案。ssi的发病率在世界范围内呈上升趋势,与之相关的发病率高,生活质量总体下降,有时甚至死亡。SSI管理的经济负担对每个国家来说都是巨大的,压力很大。脊柱手术后治疗ssi是令人望而生畏的,因为在移除植入物以清除细菌和导致脊柱不稳定的风险之间做出选择是一个难题。结论:在脊柱清洁手术中,尽管手术技术、无菌方案和预防性抗生素的作用得到了改善,但ssi的发生率仍有大幅上升。因此,预防比希望得到适当的治疗更有益。
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