A link prediction approach for drug recommendation in disease-drug bipartite network

Esra Gündogan, Buket Kaya
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引用次数: 10

Abstract

Social networks we have encountered in different areas and in different forms have a dynamic structure because the relationships they define constantly change. Link prediction is an important and effective solution to understand this dynamic nature of networks and to identify future relations. It estimates of possible future connections between nodes in the network taking advantage of network's current state. In this study, a method for link prediction in the disease-drug network is proposed. Sofar, the most of studies done is usually based on connection prediction in single mode networks. This method has been applied on a bipartite such as disease-drug network, as apart from single mode networks. To compare performance of the proposed method, four of similarity based link prediction methods has been also applied to the network. The results obtained from experiments show that the proposed method has a good percentage of success than the other similarity based link prediction methods.
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疾病-药物双部网络中药物推荐的链接预测方法
我们在不同领域和不同形式遇到的社交网络具有动态结构,因为它们定义的关系不断变化。链路预测是了解网络动态特性和确定未来关系的重要而有效的解决方案。它利用网络的当前状态估计网络中节点之间可能的未来连接。本研究提出了一种疾病-药物网络中的链接预测方法。到目前为止,大多数研究通常是基于单模网络的连接预测。除了单模网络外,该方法还应用于疾病-药物网络等二部网络。为了比较所提方法的性能,还将四种基于相似度的链路预测方法应用于网络。实验结果表明,与其他基于相似度的链路预测方法相比,该方法具有较高的预测成功率。
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