[Cell electrophoretic and absorption spectrographic investigations of the indirect effect of ultraviolet light on erythrocytes of patients with myocardial infarct and other illnesses].

Abstract

In 34 patients with myocardial infarct, 14 patients with arterial circulatory bleeding disturbances and 12 dialysis patients, blood was diluted immediately after collection by using an Eagle medium (MEM) which had been irradiated by ultraviolet rays. The erythrocytes of patients with myocardial infarct and circulatory bleeding disturbances responded with a mean increase of negative net surface loading by roughly 6% related to the controls in not-irradiated medium. In the erythrocytes of dialysis patients we found no changes of this kind. After ultraviolet irradiation the uv/vis absorption spectra of the Eagle medium showed an increase of extinction depending on the dosage in the short-wave range and a decrease in the long-wave range. Apparently, these uv-induced changes in the Eagle medium secondarily cause an increase of the surface loading of erythrocytes. In patients with arterial circulatory bleeding disturbances this effect which affects the electrostatic relations particularly in the area of terminal flows could contribute to improving the stability of suspension in the blood, thus having a therapeutic importance for these patients as far as their microcirculation is concerned.