{"title":"PHYSIOLOGIC EFFECTS OF CHRONIC EXPOSURE TO PHOSGENE IN DOGS.","authors":"R. Rossing","doi":"10.1097/00043764-196503000-00021","DOIUrl":null,"url":null,"abstract":"Recurrent exposure of dogs to phosgene gas produces a chronic obliterative bronchiolitis with a characteristic physiologic picture. After an acute phase, in which changes in elastic behavior predominate, a definite increase in lower airway resistance is seen which persists throughout the period of exposure. Accompanying this change the uniformity of distribution of inspired air is progressively disturbed as evidenced by nitrogen washout curves. In addition, microscopic changes suggestive of early, peribronchiolar emphysema are seen.","PeriodicalId":125752,"journal":{"name":"The American journal of physiology","volume":"95 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1964-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"22","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The American journal of physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1097/00043764-196503000-00021","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 22
Abstract
Recurrent exposure of dogs to phosgene gas produces a chronic obliterative bronchiolitis with a characteristic physiologic picture. After an acute phase, in which changes in elastic behavior predominate, a definite increase in lower airway resistance is seen which persists throughout the period of exposure. Accompanying this change the uniformity of distribution of inspired air is progressively disturbed as evidenced by nitrogen washout curves. In addition, microscopic changes suggestive of early, peribronchiolar emphysema are seen.
京公网安备 11010802042870号
京ICP备2023020795号-1
分享
求助内容：
应助结果提醒方式：
扫码关注我们
