Application of mathematical modeling methods and use of information technologies for research of viral hepatitis B

Abstract

It is known that the study and research of existing problems of medicine using modern information technologies is the most relevant today. Mathematical modeling of the activities of the regulatory mechanisms of living systems at the organismal, organ, cellular and molecular-genetic levels is one of the promising areas in the field of medical biology. The scientific research discusses the results of a quantitative study of the regulatory mechanisms of liver cells and hepatitis B viruses based on mathematical and computer models by using the Matlab application package. The study of the quasi-stationary state of the liver cell under the pressure of hepatitis B viruses using mathematical modeling methods is one of the urgent tasks. The use of mathematical modeling to analyze the interaction of the regulatory mechanisms of molecular genetic systems of liver cells and hepatitis B viruses makes it possible to analyze the main forms of infectious viral hepatitis B in a quasi-stationary state of liver cells. The results of a qualitative study of the equations of hepatitis B regulators in the quasi-stationary state of liver cells are presented.