The effects of cafeteria diet induced obesity on rat blood amino acid compartmentation.

Abstract

In female virgin Wistar rats, the effects of a cafeteria-diet induced obesity on blood amino acid levels and their distribution between plasma and blood cells have been studied in fed and 24-hour starved states. Cafeteria diet induced obesity provoked a decrease in total blood cell amino acid content, both in fed and starved situations when compared with controls. Whether is a causal factor for developing obesity due to imbalance in tissue amino acid supply for protein biosynthesis processes, or represents some signal related to hypothalamic control of feeding, or is a consequence of the obesity remains to be established.