Effect of conditioned medium on recovery of circulating blood cells in irradiated mice.

N Macková, P Fedorocko, P Brezáni
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Abstract

The effect of supernatant of thymus-cell conditioned medium (TCCM) on blood element recovery in peripheral blood was followed in mice exposed to a single whole body dose of 5.8 Gy of gamma radiation. As follows from our results. TCCM administered 18 h before irradiation accelerated the recovery of the reticulocyte and, in part, thrombocyte and granulocyte counts. However, no effect on the rate of lymphocyte recovery was found.

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条件培养基对辐照小鼠循环血细胞恢复的影响。
研究了胸腺细胞条件培养基(TCCM)上清液对全身单剂量5.8 Gy γ射线照射小鼠外周血血素恢复的影响。结果如下:照射前18小时给予TCCM加速网状红细胞的恢复,部分加速血小板和粒细胞计数的恢复。然而,没有发现对淋巴细胞恢复率的影响。
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