The activity of neutrophil myeloperoxidase in patients with Hodgkin's disease.

M Dabrowska, H Kemona, J Prokopowicz, A Dabrowski, S Kiluk
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Abstract

Neutrophil myeloperoxidase activity has been studied in twenty one patients diagnosed with Hodgkin's disease. The presented data indicate no differences in total MPO activity, whereas we observed some differences in the percentage of granulocytes with different degree of scores. Changes in the intensity of reaction may indicate the possibility of exocytosis as a mechanism releasing MPO from the cell to the surrounding area. In peripheral, circulating neutrophils, such a phenomenon seems to be of no avail and may disorganise anti-cancer defence.

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霍奇金病患者中性粒细胞过氧化物酶的活性。
研究了21例霍奇金病患者的中性粒细胞髓过氧化物酶活性。目前的数据表明,总的MPO活性没有差异,而我们观察到不同程度评分的粒细胞百分比有一些差异。反应强度的变化可能表明胞吐可能是一种将MPO从细胞释放到周围区域的机制。在外周,循环中性粒细胞,这种现象似乎是无用的,并可能破坏抗癌防御。
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